[HTML][HTML] Learned avoidance from noxious mechanical simulation but not threshold semmes weinstein filament stimulation after nerve injury in rats

HE Wu, G Gemes, V Zoga, T Kawano, QH Hogan - The Journal of Pain, 2010 - Elsevier
Noxious mechanical stimulation evokes a complex and sustained hyperalgesic motor
response after peripheral nerve injury that contrasts with a brief and simple withdrawal seen
after noxious stimulation in control animals or after threshold punctate mechanical
stimulation by the von Frey technique. To test which of these behaviors indicate pain, the
aversiveness of the experience associated with each was determined using a passive
avoidance test in rats after sciatic nerve ligation (SNL) or skin incision alone. After 18 days …